Which adverse effect is most commonly associated with the use of antihypertensive medications?

Postural hypotension is a significant adverse effect commonly associated with antihypertensive medications. This condition occurs when there is a sudden drop in blood pressure upon standing up, which can lead to dizziness or fainting. Antihypertensive medications, particularly those that lower blood pressure aggressively or those that act as vasodilators, can disrupt the body's ability to regulate blood flow in response to changes in position.

This side effect is particularly important for nursing assessments and patient education, as it can place patients at a higher risk for falls, especially in the elderly or those who may also be taking other medications that affect blood pressure. Monitoring for symptoms of postural hypotension, like lightheadedness or vertigo, is critical, as is encouraging patients to rise slowly from sitting or lying positions.