What condition is known to contribute to secondary hypertension?

The condition that is known to contribute to secondary hypertension is renal disease. Secondary hypertension arises from an identifiable underlying condition, and renal disease is a leading cause of this secondary hypertension. When renal function is compromised, the kidneys may not effectively regulate blood pressure by controlling fluid balance and electrolyte levels, which can lead to increased blood volume and pressure.

Additionally, conditions such as renal artery stenosis can lead to increased renin secretion, ultimately resulting in elevated angiotensin II levels, promoting vascular constriction and fluid retention, thereby raising blood pressure.

While arterial vasoconstriction is a mechanism that can contribute to hypertension, it is not classified under secondary hypertension since it is often a result of various underlying conditions that may not be directly reporting to a specific disease process. Acid-base imbalances and calcium deficits do not directly lead to the same degree of impact on blood pressure regulation as renal disease does, thus they are less relevant in this context.